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The deficiency of some vitamins such as folate, vitamin B12, and vitamin B6 increases the serum and tissue levels of homocysteine

Lipase inhibitors such as alli or Xenical (orlistat) have been associated with rare liver injury and patients should be alert for signs of liver disease such as itching, yellow skin or eyes (jaundice), stomach pain, loss of appetite, pale or tar-colored stools, brown-colored urine (due to excess bilirubin in the urine)

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In cases of more advanced osteoarthritis, the use of stem cells can help to replace cells that were damaged