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Development of animal models is particularly urgent for concussion/mild TBI and brain injuries because of blast as well as for repetitive injuries

Nevertheless, the final cohort of 35 patients was deemed adequate for exploratory analysis based on clinical relevance, statistical stability, and consistency with previous studies on ocular surface changes in diabetic populations

[1] [3] Patients should be counseled to maintain consistent hydration throughout treatment, aiming for adequate daily fluid intake unless otherwise restricted by medical conditions

Alcohol increases CYP2E1 enzyme activity while depleting glutathione , the compound that neutralizes acetaminophens toxic byproduct NAPQI