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First isolated from the cerebral venous blood of rabbits in 1977, this nine-amino-acid peptide has captured the attention of researchers worldwide for its remarkable effects on sleep regulation, stress response, and neuroendocrine function

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MG-induced DNA damage plays a central role in initiating apoptosis.MG induces DNA strand breaks through the formation of adducts (e.g., MGdG) and cross-linking structures with DNA, activating the intracellular DNA damage response, and triggering apoptosis by cell cycle arrest when the damage exceeds the cellular ability to repair it (104)

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