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doi:10.2215/CJN.07170622 Perkovic V, Tuttle KR, Rossing P, et al

Pediatric use: Indications and dosage guidelines for children use, have been established over 15 years

Many basal insulin plans start conservatively and adjust in small steps

Tirzepatide (Zepbound) follows a similar four-week interval for dose increases, starting at 2.5 mg and moving up through several steps to a maximum of 15 mg