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Probiotic supplementation may improve body weight, BMI, fasting glucose, insulin resistance (HOMA-IR), lipid profiles (triglycerides and very low-density lipoprotein (VLDL)-cholesterol), inflammatory markers such as C-reactive protein (CRP), and oxidative stress indicators including malondialdehyde (MDA), total antioxidant capacity (TAC), and glutathione (GSH), and hormonal parameters (total testosterone, SHBG), while also alleviating hirsutism in PCOS patients (105, 106)

INF-A use is associated with malaise, flulike symptoms, fever, and myalgia

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Silencing TFRC, the gene encoding TFR 1, can inhibit erastin-induced ferroptosis 25 , while heme oxygenase-1 (HO-1) can accelerate erastin-induced ferroptosis by supplementing iron 26