The prednisolone, active metabolite of the prednisone, diffuses through the cell membrane, where it binds to the specific cytoplasmic receptors
American Journal of Epidemiology 181(6): 374384
148 In a small randomized controlled trial that enrolled 17 participants diagnosed with NAFLD, drinking a catechin-enriched green tea providing 1,080 mg green tea catechin daily was found to have multiple positive effects: after 12 weeks, those who received the high-catechin tea had improvement in indirect measures of liver steatosis, lower body fat percentage, and decreased levels of ALT (a liver enzyme, high levels of which can indicate hepatocyte injury) and a marker of oxidative stress (urinary 8-isoprostane) compared with those who received a low-catechin tea or placebo
However, tirzepatide has been associated with serious gastrointestinal adverse events in some patients, including acute pancreatitis, gallbladder disease, and intestinal obstruction