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The nuance is that metabolic rate is lower after menopause, which means the caloric deficit produced by appetite suppression may translate to somewhat slower absolute weight loss compared to premenopausal women

PMID: 171 LooRLChanQNicholsonJKHolmesE

By enhancing insulin production when blood sugar levels are high, semaglutide helps the body efficiently manage glucose and prevent excessive spikes

In contrast, Noom states that their dosing starts at 25% or less of the standard 0.25 mg dose and escalates at a personalized rate. While microdosing GLP-1 medications may provide a more personalized experience, there are still questions regarding the safety of this practice as there are currently no published studies on the process, and the microdoses may come from a compounding pharmacy