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Description

This is partly genetic

Actionable Next Steps for Researchers: Prioritize Monotherapy Research: Continue to focus on understanding the individual properties and safety profiles of MOTS-c and Retatrutide through well-designed preclinical and clinical studies

Primary and immortalised adipocyte models document effects on lipolysis (enhanced by glucagon receptor activation), browning markers (uncoupling protein 1, PGC-1), and thermogenic gene expression