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Importantly, recent reports showed that about 211% of patients with COVID-19 had underlying chronic liver disease ( The above and other reports led Roberts et al

In patients with mCRPC and no previous chemotherapy, cabazitaxel and docetaxel appeared to provide similar results with respect to OS.[64] In the FIRSTANA trial (NCT01308567), 1,168 men with mCRPC were randomly assigned in a 1:1:1 ratio to receive cabazitaxel 20 mg/m2, cabazitaxel 25 mg/m2, or docetaxel 75 mg/m2 IV every 3 weeks (plus prednisone 10 mg PO qd) until disease progression

This phenomenon could be correlated with the extent of their initial weight loss [34]

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