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This process occurs primarily in the liver and adipose tissue and uses acetyl-CoA for fatty acid synthesis, forming TG ( 4 PQQ and epigenetic obesity Maternal obesity during pregnancy is a risk factor for programming obesity in the offspring ( 5 PQQ and the gut microbiota The gut microbiota composition can influence obesity risk and overall health ( Bacteroidetes and increase in Firmicutes observed in the offspring (Figure 1B)