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Description

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These drugs work by mimicking the action of natural GLP-1 hormone, which stimulates insulin secretion in response to food intake, suppresses glucagon release, slows gastric emptying, and reduces appetite

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New England Journal of Medicine (2021) This landmark phase 3 trial evaluated semaglutide 2.4mg weekly versus placebo for weight management in 1,961 adults with obesity or overweight with comorbidities

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Importantly, muscle inactivity is metabolically active rather than neutral

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