In particular, the Nlrp3 inflammasome is a cytosolic multiprotein complex expressed in immune/inflammatory cells as well as cardiovascular system cells, including endothelial cells, myofibroblasts/fibroblasts, and cardiomyocytes, which, through the processing and release of interleukin (IL)-1 and IL-18 and the induction of cell death processes (pyroptosis, apoptosis, and necroptosis), plays a key role in the maintenance of host homeostasis and in sustaining the pathophysiological events underlying CVDs (48)
Hunt, K.) 103157 (Academic, New York, 1980) Nicholls, J
Research shows that curcumin supplementation lowers inflammatory markers, boosts antioxidant capacity, and enhances skin parameters by modulating oxidative stress pathways [62,63,64]
Ya asitleri hcre iine girdiinde, mitokondrinin ift katmanl zarn kendi balarna geemezler