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Hit compounds identified from the high-throughput screen were validated via dose-response inhibition assays and further evaluated for cytotoxicity in MCF-7 estrogen and progesterone receptor-positive breast cancer cells and MDA-MB-231 triple-negative breast cancer cells

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Physically, reducing body fat can lead to improved cardiovascular health, lowered blood pressure, decreased risk of chronic diseases such as diabetes and certain cancers, improved mobility and joint health, and increased energy levels