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retatrutide peptide vs tirzepatide

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We achieved this by using caloric restriction with the goal similar changes in weight and body composition in the two groups so that we could adequately evaluate metabolic adaptation

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Tirzepatide vs semaglutide 1 mg in T2D SURPASS-2, HbA1c -2.01/-2.24/-2.30 pp, weight dose-responsive while HbA1c saturates: Frias NEJM 2021

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