oral glp-1 medications approved FDA approves Foundayo, an alternative to Wegovy and Ozempic Oral GLP-1 Therapy for Obesity

For moderate weight loss with minimal side effects, a maintenance dose of 4mg provides 17% body weight reduction with a tolerable side effect profile

One possibility is that bile acids act through both FXR and TGR5 to mediate the metabolic success of surgery but that differences between studies reflect variation in the ability of the FXR system to compensate for the loss of TGR5

While originally designed for Type 2 diabetes, GLP-1 drugs are now used for obesity, PCOS, cardiovascular protection, liver disease, and even neurological disorders

Therefore, for now, it is better to focus on the conclusions that tirzepatide is safe from a cardiovascular perspective