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Glucagon-like peptide 1 receptor agonists and risk of diabetic retinopathy complications: cohort study in nationwide registers from two countries

Furthermore, the majority of our studies involve acute metformin administration and so our data cannot rule out the possibility that signalling through the GLP1R might contribute more substantially to the chronic glucose-lowering actions of metformin in more severe models of hyperglycaemia

GLP-1 RAs are contraindicated during pregnancy due to limited safety data and potential embryofetal risk

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