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These interventions aim to deliver targeted symptom relief directly within the joint space, with the principal agents including corticosteroids, hyaluronic acid (HA), and emerging biologics such as platelet-rich plasma (PRP) and cell-based products (Wehling et al., 2017

2 CONCLUSION: GLP-1R agonists have the potential, at least in theory, to regulate platelet activation directly through the effect on platelet function and indirectly through the control of body weight and metabolism

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