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The following acquisition parameters were applied for all samples: data dependent acquisition (DDA) in positive ion mode with survey scan of 60,000

Cells (1 10 5 cells per well) were incubated for 1, 2, 4, and 6 h with samples at a final concentration of 0.5 g/mL of Cy5.5

Animal reproduction studies showed that semaglutide and tirzepatide affected pancreatic and metabolic organ development in rodents and primates at doses comparable to human weight loss treatment

Similarly, activated microglia contribute to oxidative stress by upregulating NADPH oxidase 2 (NOX2), which generates O , and inducible nitric oxide synthase (iNOS), which produces nitric oxide (NO)