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More and more research reveals that neurovascular disorders play an important role in the pathophysiology of brain diseases throughout life, such as neurodevelopmental and neurodegenerative disorders (Ouellette et al

Site rotation, proper injection technique, and using appropriately sized needles minimize these occurrences

the present invention provides copper peptide reservoir in gel form wherein gelling agent selected makes sustained release of copper peptide over considerable long time such that the patch shall not be changed over 12 hrs, preferably over 24 hrs and most preferably over 48 hrs